What protects the stomach's lining from hydrochloric acid?


Posted On May 10 2010 by

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An H. pylori infection can start a lesion that HCl and digestive enzymes can exacerbate, resulting in an ulcer.

pylori and inflammation of the stomach lining, gastritis, and ulcers. In fact, new research suggests that the bacteria may also be linked to stomach cancer. The upper part of the stomach, however, is lined by squamous mucosa and doesn’t have the same protection from the acid.

Gastric Secretion

The serosa has a smooth, slippery surface and secretes a thin, watery secretion known as serous fluid. The smooth, wet surface of the serosa helps to protect the stomach from friction as it expands with food and moves to mix and propel the food. The stomach is a rounded, hollow organ located just inferior to the diaphragm in the left part of the abdominal cavity. Located between the esophagus and the duodenum, the stomach is a roughly crescent-shaped enlargement of the gastrointestinal tract. The inner layer of the stomach is full of wrinkles known as rugae (or gastric folds).

Physiology of the Stomach and Gastric Juices

When prostaglandins are blocked, less gastric mucus is secreted, cellular junctions become less tight and mucosal blood flow is less adequately maintained. This makes the mucus layer less effective at protecting the stomach epithelium as well as less effective at managing any subsequent damage to the epithelium.

Your stomach secretes hydrochloric acid, but the pH of your stomach isn’t necessarily the same as the pH of the acid. It is an interesting fact that many enzymes in the digestive system are initially produced in their inactive form.

This prevents additional chyme from being released by the stomach before the duodenum is ready to process it. Why does the mucosal barrier break down? A number of factors can interfere with its ability to protect the stomach lining.

In summary, HCl in the stomach lumen accomplishes four things. It helps break down ingested tissues for attack by digestive enzymes; it provides the correct pH for the action of those enzymes; it converts a catalytically inactive proenzyme to an active enzyme (as we just saw); and it destroys invading microorganisms in the stomach contents. Your diet is important for your digestive and overall health. What you put in your stomach can make a difference in the health of your digestive system. For instance, some forms of gastritis are caused by drinking alcohol too often or too much at one time.

the stomach lining is protected from the stomach acid by

Last Updated on: September 26th, 2019 at 9:18 pm, by


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