Preparation and Property of Xylan/Poly

Posted On Nov 10 2009 by

This salting-out taste-masking system is used for taste-masking of solifenacin succinate in a launched oral disintegrating tablet. The concept, in vitro drug release data, taste-masking sensory tests, and verification in the clinical studies indicate that this system is versatile and applicable to other drugs that require rapid release for absorption and therapeutic effect after taste-masking. Coating of water-insoluble polymers on drug’s particles without resin has no driving force for promoting drug release and cannot release drugs completely in the gastrointestinal fluids. The drug-resin complexed DDSs have the significant advantage of complete drug release caused by the ionic equilibrium. 28. A …