Gastrointestinal problems in hypermobile Ehlers-Danlos syndrome and hypermobility spectrum disorders – The Ehlers-Danlos Support UK


Posted On Mar 16 2010 by

After 15 plus years of stomach problems and many years of gastroenterologist consultation, my doctor finally took me and my symptoms enough to do further testing seriously. Emptying tests revealed I wasn’t emptying after 4 hours and an EGG test was also abnormal.

The hospitals look at me like I’m crazy or something (I’m talking about the emergency rooms). There are probably things I have forgotten to mention here. Functional gastrointestinal disorders (FGIDs), including functional dyspepsia (FD), are common chronic disorders even in the younger population. Physical activity is advocated for patients with FGIDs, although the evidence is insufficient. We investigated the association between the intensity of regular exercise and gastric emptying to determine the effect of physical activity on dyspeptic symptoms.

Patients with autonomic nervous system dysfunction were then analyzed and compared by means of existence of delayed gastric emptying and gastrointestinal symptoms. Autonomic neuropathy is widely recognized to be associated with upper gastrointestinal symptoms and abnormal (i.e., rapid or slow) gastric emptying. While patients with postural orthostatic tachycardia syndrome (POTS) may also have gastrointestinal symptoms, our understanding of gastric-emptying disturbances in POTS is very limited.

excess stomach acid cause gastroparesis symptoms dysautonomia

However wherever possible or relevant this leaflet will give additional information about how the other types of EDS can affect the gut. Many specialists in this field consider hEDS to be a continuum of joint hypermobility syndrome (JHS) – or what are now called the ‘hypermobility spectrum disorders’ (HSD). In this article hEDS will also refer to HSD. In hEDS the main identifiable factors are the presence of skin elasticity or ‘stretchiness’ and hyper-flexible joints, which means that joints can move beyond the ‘normal’ limits.

  • I’m 90% better with medication though I can have an infrequent episode, but they are few and between far.
  • Despite research evidence that clinical observations (whether they be symptoms or routine vital signs) should not be the sole basis for the diagnosis of cardiovascular autonomic dysfunction, screening for abnormalities is done infrequently.
  • I had been dealing with gastrointestinal problems for years before the diagnosis; most of these were nausea, vomiting, and a developed aversion to food.
  • Preliminary experience continues to suggest that autonomic dysfunction might be a contributing factor to upper digestive tract symptoms, but further research is needed to understand if this is the full case.
  • Imaging tests and physiological measurements are used to determine the functioning of the stomach and the rate of gastric emptying.

It can affect blood pressure, temperature control, digestion, bladder function and even sexual function. A computerized diagnostic index was used to identify all patients, 18-70 years old, who underwent single-photon emission computed tomography (SPECT) to assess gastric accommodation at Mayo Clinic Rochester over a 3-year period. Demographics, clinical features, and results of diagnostic testing, including scintigraphic gastric emptying, were extracted from the electronic record. The aim was to assess relative contributions of gastric volumes (GV) and gastric emptying (GE) to meal size and postprandial symptoms in patients with functional dyspepsia. These findings indicate that autonomic symptoms and deficits are common in diabetes, but mild in severity, and that the correlation between symptom deficits and scores is overall weak in mild diabetic neuropathy, emphasizing the need to separately evaluate autonomic symptoms..

Belching is perhaps more common in the older age groups and is consequent on oesophago-gastric dysmotility.

I am 57, type 2 diabetic. I have had gastroparesis for years but it”s really getting me down. For a few days I’m really constipated and bloated and vomit when I eat anything, . week or two I have severe stomach cramps and uncontrollable diarrhea then for the next. . I bleed a lot from the back end also.} I”ve had numerous tests and medication but nothing works. I”m scared to go out and have to wear a nappy. On top of this I have severe narcolepsy and cataplexy but that”s another story.

last, we compared several methods of analyzing gastric emptying data obtained using the gamma-camera. Eighteen healthy control subjects and 16 insulin-dependent diabetics with neuropathy were investigated. Ten of the patients suffered from chronic nausea and vomiting; the remaining 6 served as disease controls. Gastric emptying of solid and liquid meals could best be described by the slopes of two linear components and their intercept.

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