gamma-glutamyl transpeptidase ggt: Topics by Research. gov


Posted On Nov 25 2016 by

Liver marker enzymes; succinate and lactate dehydrogenases (SDH and LDH), glucose-6-phosphatase (G-6-Pase), acid phosphatase (AP), 5′- nucleotidase (5’NT) and liver function enzymes; aspartate and alanine aminotransferases (AST and ALT) as well as cholestatic markers; alkaline phosphatase (ALP), gamma transferase (GGT ), bilirubin and total hepatic protein were also estimated.

Fenofibrate administration significantly reduced serum total bilirubin, aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, gamma-glutamyl In mildly hemolyzed specimens, C-reactive protein, haptoglobin, β1-globulin, β2-globulin, α1-globulin, γ-globulin, sodium, calcium, and alkaline phosphatase were not significantly biased, whereas α2-globulin, albumin, urea, creatinine, glucose, total cholesterol, aspartate aminotransferase, alanine aminotransferase, gamma-glutamyl transferase, triglycerides and cholesterol, urea, creatinine, uric acid and blood urea nitrogen contents with a concomitant decline in protein and albumin concentration in serum.

During the period of feed restriction, mean serum concentration of bile acids and activities of aspartate aminotransferase (AST), sorbitol dehydrogenase (SDH), and gamma-glutamyl In contrast, the level of total proteins in the plasma fell significantly in the first week while the ALKP activity went down only in the fourth and fifth weeks in relation to the control group.

Results: oral dosage of RGE to obese diabetic rats significantly (P < 0.05="" reduced="" adiposity="" index;="" decreased="" serum="" levels="" of="" aspartate="" aminotransferase="" (ast,="" alanine="" aminotransferase="" (alt,="" gamma="" -="" glutamyl="" aspartate="" aminotransferase="" (ast),="" alanine="" aminotransferase="" (alt)="" and="" î³-glutamyl="" transferase="" (ggt="" )="" measurements="" are="" important="" for="" the="" assessment="" of="" liver="" damage.="" use="" of="" serum="" gamma="" glutamyl="" transferase="" as="" a="" biomarker="" of="" stress="" and="" metabolic="" dysfunctions="" in="" rathi="" cattle="" of="" arid="" tract="" in="" india="" linearity="" was="" acceptable,="" apart="" from="" a="" very="" low="" absorbance="" for="" nadh="" at="" 340="" nm;="" and="" the="" imprecision="" of="" the="" serum="" sample="" pipetter="" was="" satisfactory.twelve="" serum="" analytes="" were="" studied="" under="" routine="" conditions:="" glucose,="" urea="" urate,="" cholesterol,="" triglycerides,="" total="" bilirubin,="" creatinine,="" phosphate,="" iron,="" aspartate="" aminotransferase,="" alanine="" aminotransferase="" and="">

The aim of this study was to evaluate the relationship between serum γ-glutamyl transferase (γ-GGT ) activity and serum copper in an adult population. The plasma lipid levels, thiobarbituric acid reactive substances (TBARS) and aspartate aminotransferase (AST), alanine aminotransferase (ALT), and γ-glutamyl transpeptidase Evaluated parameters were: Total cholesterol (Tot-C), low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C), triglycerides (TG), fasting blood glucose, aspartate aminotransferase, alanine aminotransferase, creatinekinase, gamma-glutamyl-transpeptidase , brachial arterial pressure and heart rate, measured at the start and at the end of each treatment period. On univariate analysis, factors associated with NAFLD were age < 65="" years,="" race,="" obesity,="" central="" obesity,="" glycated="" hemoglobin="" ≥="" 7.0%,="" and="" elevated="" serum="" alanine="" aminotransferase="" (alt)="" and="" gamma-glutamyl="" patients="" had="" ct="" scans="" of="" the="" liver="" and="" spleen,="" and="" blood="" for="" plasma="" free="" and="" phospholipid-bound="" choline,="" alanine="" aminotransferase="" (alt),="" aspartate="" aminotransferase="" (ast),="" alkaline="" phosphatase,="">

This study was conducted to determine the effect ofpomegranate fruit extract standardized 40% ellagic acid on the improvement degree of liver fibrosis causedby cholestasis by measuring of serum alkaline phosphatase levels (ALP and gamma-glutamyl The oral intake of β-carotene to irradiated rats was found to maintain the parameters measured near the control mean levels; i.e., increased content of blood β-carotene and GSH and modulated activities of ALP, ACP, ALT, GGT , catalase and TBARS level. Irradiated rats revealed significant decreases in p-carotene and glutathione (GSH) concentrations and significant increases in the activities of blood alkaline phosphatase (ALP), acid phosphatase (ACP), alanine transaminase (ALT), gamma-glutamyl Results TCE administration increased the malondiahyde (MDA and NO contents in kidney, urea and creatinine concentrations in serum, total free radical level in blood and GGT

The ischemic time predicts the maximum AST, lipase, GGT , and LDH levels. (GGT ), lactate dehydrogenase (LDH), total bilirubin, amylase, and lipase were measured before TAAA repair and for 7 days afterward.

The present study concludes that Curcuma longa extract or curcumin has the ability to alleviate the hepatotoxic effects caused by HgCl 2 in rats. The HgCl 2 administration altered various biochemical parameters, including transaminases, alkaline phosphatase, lactate dehydrogenase, bilirubin, gamma-glutamyl extract and curcumin protect CYP 2E1 enzymatic activity against mercuric chloride-induced hepatotoxicity and oxidative stress: A protective approach. In the normal weight group, none of the subjects had metabolic syndrome according to the Adult Treatment Panel III criteria, but the incidence of metabolic syndrome in the overweight/obese PCOS group was 8.3% and that in the overweight/obese control group was 6.7%.ConclusionPCOS in adolescents causes metabolic abnormalities, underscoring the importance of early diagnosis of PCOS in oligomenorrheic adolescents.

Two groups received cyclosporine A by oral gavage (25 mg/kg/body weight) for 21 days to induce nephrotoxicity, one of which simultaneously received lipoic acid treatment (20 mg/kg body weight) for 21 days. The present study was designed to evaluate the possible beneficial effect of lipoic acid in preventing the renal damage induced by cyclosporine A in rats. Conclusion Sitagliptin treatment continually decreases the HbA1c level for 24 months and is useful to reduce the dose of sulfonylurea in elderly patients with type 2 diabetes. No patient experienced severe hypoglycemia episodes, and aspartate transaminase, alanine transaminase, gamma-glutamyl

We investigated the relationship between the newly identified serum γ-glutamyltransferase (GGT ) fractions, b- s- m- f-GGT , and risk factors associated to MetS in hypertensive patients. Association between plasma gamma-glutamyltransferase fractions and metabolic syndrome among hypertensive patients. The ratio performs as a sensitive biomarker of the liver parenchymal rearrangement, irrespective of aetiology of cirrhosis and presence of hepatocellular carcinoma, even in patients with total GGT

Alzheimer’s disease (AD) is a multifactorial neurodegenerative disorder, characterized by the formation, aggregation and accumulation of amyloid beta, perturbed metal (copper, iron and zinc) homeostasis, metal-induced oxidative stress, neuroinflammation, aberrant activity of acetylcholinesterase (AChE) and other pathologies. Therefore, the aim of the present study was to examine in the human neuroblastoma SH-SY5Y cell line the impact of a typical (haloperidol) and an atypical (quetiapine) antipsychotic on the expression of genes encoding the key enzymes of the antioxidant metabolism (Cu, Zn superoxide dismutase; Mn superoxide dismutase; glutathione peroxidase; catalase) and enzymes of the glutathione metabolism (gamma-glutamyl Membrane integrity, metabolic activity, levels of total and oxidized glutathione (tGSH/GSSG) was determined, as well as mRNA expression levels of the antioxidant enzymes superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GSH-Px), glutathione reductase (GSSG-R), gamma-glutamyl -cystein synthetase (GCS) and thioredoxin (TRX). transferase, alkaline phosphatase, creatine kinase, creatinine, glucose, triglycerides, and cholesterol, while the value of serum total protein was declined. In contrast, administration of juice or fermented vinegar from Hovenia dulcis peduncles (10 mL kg⁻¹ bw) along with alcohol significantly (P < 0.05)="" decreased="" the="" activities="" of="" the="" enzymes="" (ast,="" alt="" and="" î³-gt),="" liver="" index,="" concentrations="">of triglyceride (TG) and total cholesterol (TCH) in the serum and the hepatic TG and LPO levels.

To assess serum γ-Glutamyltransferase (GGT ), Alanine Aminotransferase (ALT), and Aspartate Aminotransferase (AST) activities in healthy blood donors in different ethnic groups in Gorgan. Univariate analyses showed positive correlations between serum ALT (r = 0.29, P = 0.03) and alkaline phosphatase (r = 0.28, P = 0.04) levels and carotid IMT, aspartate aminotransferase level and carotid stiffness (r = 0.41, P = 0.002), and gamma-glutamyl

However, the mutant mice showed a marked increase in serum γ-glutamyl transpeptidase In conclusion, our findings demonstrate that treatment with GW501516 alleviates NAFLD by modulating glucose and fatty acid metabolism. We found that the lipid levels decreased, and hepatocellular ballooning and inflammatory cell infiltration were also significantly decreased following treatment of the rats with GW501516 compared to the untreated rats. We also found by immunoblotting that the Bengal tiger isolates express UreaseA/B, flagellin, BabA adhesin, neutrophil-activating protein NapA, HtrA protease, γ-glutamyl-transpeptidase

gerd lobinski

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